2012•Cancer CellOpen access

The ALKF1174L Mutation Potentiates the Oncogenic Activity of MYCN in Neuroblastoma

Teeara Berry, William Luther, Namrata Bhatnagar, Yann Jamin, Evon Poon, Takaomi Sanda, De‐Sheng Pei, Bandana Sharma, Winston Vetharoy, Albert Hallsworth, Zai Ahmad, Karen T. Barker, Lisa A. Moreau, Hannah T. Webber, Wenchao Wang, Qingsong Liu, Antonio R. Pérez‐Atayde, Scott J. Rodig, Nai‐Kong V. Cheung, Florence I. Raynaud, Bengt Hallberg, Simon P. Robinson, Nathanael S. Gray, Andrew D.J. Pearson, Suzanne A. Eccles, Louis Chesler, Rani E. George

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Key concepts: Neuroblastoma, Crizotinib, Cancer research, PI3K/AKT/mTOR pathway, Protein kinase B, Biology, Targeted therapy, Mutation