2003Infection and ImmunityOpen access

Neisseria meningitidis RTX Proteins Are Not Required for Virulence in Infant Rats

Stanislav Forman, Irena Linhartová, Radim Osička, Xavier Nassif, Peter Šebo, Vladimir Pelicic

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Abstract

RTX cytotoxins play an important role in virulence of numerous gram-negative pathogens. Unexpectedly, however, we show here that the RTX proteins of Neisseria meningitidis are dispensable for virulence in the infant rat model of infection.

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What this paper is about

RTX cytotoxins play an important role in virulence of numerous gram-negative pathogens. Unexpectedly, however, we show here that the RTX proteins of Neisseria meningitidis are dispensable for virulence in the infant rat model of infection.

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OpenAlex reports 26 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

RTX cytotoxins play an important role in virulence of numerous gram-negative pathogens. Unexpectedly, however, we show here that the RTX proteins of Neisseria meningitidis are dispensable for virulence in the infant rat model of infection.

Key concepts: Virulence, Neisseria meningitidis, Biology, Microbiology, Neisseria, Bacterial protein, Virology, Bacteria

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