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Development of an animal model for neuroleptic malignant syndrome: heat-exposed rabbits with haloperidol and atropine administration exhibit increased muscle activity, hyperthermia, and high serum creatine phosphokinase level

Hisashi Tanii, Norio Taniguchi, Hisayoshi Niigawa, Takayoshi Hosono, Yasumitsu Ikura, Sakae Sakamoto, Takashi Kudo, Tsuyoshi Nishimura, Masatoshi Takeda

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Key concepts: Haloperidol, Atropine, Hyperthermia, Creatine kinase, Medicine, Neuroleptic malignant syndrome, Animal model, Anesthesia

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Development of an animal model for neuroleptic malignant syndrome: heat-exposed rabbits with haloperidol and atropine administration exhibit increased muscle activity, hyperthermia, and high serum creatine phosphokinase level — Research Paper | ScholarLens