1989•Acta Obstetricia Et Gynecologica ScandinavicaRequires access

Endodermal Sinus Tumor Treated with High Dose Cisplatin

Finn Edler von Eyben, Mohammed Z. Siddiqui, S Thunold

Abstract

A woman with an endodermal sinus tumor of the ovary stage IV obtained a short but complete remission after treatment with vinblastine, bleomycin and standard dose cisplatin. A second complete remission for 42+ months was obtained with a regimen of vinblastine, bleomycin, etoposide, and high dose cisplatin. This result suggests a dose-response relationship for cisplatin in ovarian germ cell tumors.

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Key concepts: Bleomycin, Vinblastine, Etoposide, Cisplatin, Endodermal sinus tumor, Medicine, Germ cell tumors, Regimen