ScholarLens Back to search
1986•FEBS LettersOpen access

Characteristic anticodon sequences of major tRNA species from an extreme thermophile, Thermus thermophilus HB8

Miki Hara‐Yokoyama, Shigeyuki Yokoyama, Tatsuo Watanabe, Kimitsuna Watanabe, Masako Kitazume, Yasue Mitamura, Toshie Morii, Seizo Takahashi, Yoshiyuki Kuchino, Susumu Nishimura, Tatsuo Miyazawa

Open full text 10 citations

Abstract

Major species of tRNAGlu, tRNALys, tRNAVal, tRNAAla, tRNASer and tRNAArg were purified from Thermus thermophilus HB8, and their anticodon sequences were found to be CUC, CUU, CAC, GGC, GGA and CCG, respectively, with unmodified G or C as the first letter. These anticodons exactly correspond to the codons as used most frequently among synonymous codons in the structural genes of extreme thermophiles. The stable complexes of these anticodons (in particular, GGN or CCN) with their corresponding codons probably contribute to the correct protein biosynthesis in extreme thermophiles at high temperature.

Open-access reader

About this research paper

What this paper is about

Major species of tRNAGlu, tRNALys, tRNAVal, tRNAAla, tRNASer and tRNAArg were purified from Thermus thermophilus HB8, and their anticodon sequences were found to be CUC, CUU, CAC, GGC, GGA and CCG, respectively, with unmodified G or C as the first letter. These anticodons exactly correspond to the codons as used most frequently among synonymous codons in the structural genes of extreme thermophiles. The stable complexes of these anticodons (in particular, GGN or CCN) with their corresponding codons probably contribute to the correct protein biosynthesis in extreme thermophiles at high temperature.

Why it matters

OpenAlex reports 10 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Major species of tRNAGlu, tRNALys, tRNAVal, tRNAAla, tRNASer and tRNAArg were purified from Thermus thermophilus HB8, and their anticodon sequences were found to be CUC, CUU, CAC, GGC, GGA and CCG, respectively, with unmodified G or C as the first letter. These anticodons exactly correspond to the codons as used most frequently among synonymous codons in the structural genes of extreme thermophiles. The stable complexes of these anticodons (in particular, GGN or CCN) with their corresponding codons probably contribute to the correct protein biosynthesis in extreme thermophiles at high temperature.

Key concepts: Thermus thermophilus, Transfer RNA, Thermophile, Thermus, Biology, Genetics, Biochemistry, Gene

Related papers

Related paper 1Related paper 2
Back to paper searchBrowse research topicsOriginal source
Characteristic anticodon sequences of major tRNA species from an extreme thermophile, Thermus thermophilus HB8 — Research Paper | ScholarLens