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2013•Journal of Rheumatic DiseasesOpen access

A Case of Overlap Syndrome of Rheumatoid Arthritis and Polymyositis with the Involvement of Upper Pharyngeal Muscles

Won Seok Jang, So Mi Kim, Seung‐Jae Hong, Sanghoon Lee, Ran Song, Hyung-In Yang, Yeon-Ah Lee

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Abstract

An overlap syndrome is a combination of major features of more than one connective tissue diseases which is presented in the same patient.An overlap syndrome of rheumatoid arthritis (RA) and polymyositis (PM) which involved the upper pharyngeal muscle has not been reported in Korea.Herein, we report a rare case of a patient with a long-history RA presenting proximal muscle weakness and swallowing difficulty, who was successfully treated with a high-dose of corticosteroid, azathioprine and tacrolimus.

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An overlap syndrome is a combination of major features of more than one connective tissue diseases which is presented in the same patient.An overlap syndrome of rheumatoid arthritis (RA) and polymyositis (PM) which involved the upper pharyngeal muscle has not been reported in Korea.Herein, we report a rare case of a patient with a long-history RA presenting proximal muscle weakness and swallowing difficulty, who was successfully treated with a high-dose of corticosteroid, azathioprine and tacrolimus.

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Available abstract

An overlap syndrome is a combination of major features of more than one connective tissue diseases which is presented in the same patient.An overlap syndrome of rheumatoid arthritis (RA) and polymyositis (PM) which involved the upper pharyngeal muscle has not been reported in Korea.Herein, we report a rare case of a patient with a long-history RA presenting proximal muscle weakness and swallowing difficulty, who was successfully treated with a high-dose of corticosteroid, azathioprine and tacrolimus.

Key concepts: Polymyositis, Medicine, Rheumatoid arthritis, Overlap syndrome, Tacrolimus, Azathioprine, Dermatology, Connective tissue

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A Case of Overlap Syndrome of Rheumatoid Arthritis and Polymyositis with the Involvement of Upper Pharyngeal Muscles — Research Paper | ScholarLens