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Plasmapheresis in fulminant acute disseminated encephalomyelitis

Daniel Kanter, D. Horensky, Reisa A. Sperling, J Kaplan, Marie E. Malachowski, W. H. Churchill

Open publisher page 149 citations

Abstract

We describe two patients with fulminant acute disseminated encephalomyelitis (ADEM) treated with plasmapheresis after they failed to improve on steroids. Both patients improved concomitant with the plasma exchange. These are the first reported cases of fulminant ADEM with extensive white matter abnormalities on imaging studies treated with a regimen of plasmapheresis and steroids. Plasmapheresis may be beneficial in this disorder.

About this research paper

What this paper is about

We describe two patients with fulminant acute disseminated encephalomyelitis (ADEM) treated with plasmapheresis after they failed to improve on steroids. Both patients improved concomitant with the plasma exchange. These are the first reported cases of fulminant ADEM with extensive white matter abnormalities on imaging studies treated with a regimen of plasmapheresis and steroids. Plasmapheresis may be beneficial in this disorder.

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OpenAlex reports 149 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

We describe two patients with fulminant acute disseminated encephalomyelitis (ADEM) treated with plasmapheresis after they failed to improve on steroids. Both patients improved concomitant with the plasma exchange. These are the first reported cases of fulminant ADEM with extensive white matter abnormalities on imaging studies treated with a regimen of plasmapheresis and steroids. Plasmapheresis may be beneficial in this disorder.

Key concepts: Acute disseminated encephalomyelitis, Plasmapheresis, Fulminant, Medicine, Neurology, Encephalomyelitis, Regimen, Pediatrics

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