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2006•Taiwanese Journal of Obstetrics and GynecologyOpen access

Concurrent Use of Mifepristone and Misoprostol for Early Medical Abortion

Yiu‐Tai Li, Fumin Chen, Tien-Hui Chen, Shu-Ching Li, Min-Lung Chen, Tsung‐Cheng Kuo

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Abstract

OBJECTIVE: This study was designed to evaluate the efficacy of using mifepristone and misoprostol concurrently for early medical abortion. MATERIALS AND METHODS: A total of 90 women with undesired pregnancies <or= 49 days' gestation were enrolled. All women concurrently received oral mifepristone 200 mg and vaginal misoprostol 800 microg. Follow-up evaluation with transvaginal ultrasonography was performed 4 days and 2 weeks after treatment. RESULTS: The complete abortion rate was 97.8% (88/90 women). The mean induction to abortion interval was 5.5 hours. The mean bleeding duration was 11.8 days. Patients found the side effects acceptable and reported a 91.1% (82 patients) satisfaction rate. CONCLUSION: Concurrent administration of oral mifepristone and vaginal misoprostol is an efficacious regimen for medical abortion of pregnancies

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OBJECTIVE: This study was designed to evaluate the efficacy of using mifepristone and misoprostol concurrently for early medical abortion. MATERIALS AND METHODS: A total of 90 women with undesired pregnancies <or= 49 days' gestation were enrolled. All women concurrently received oral mifepristone 200 mg and vaginal misoprostol 800 microg. Follow-up evaluation with transvaginal ultrasonography was performed 4 days and 2 weeks after treatment. RESULTS: The complete abortion rate was 97.8% (88/90 women). The mean induction to abortion interval was 5.5 hours. The mean bleeding duration was 11.8 days. Patients found the side effects acceptable and reported a 91.1% (82 patients) satisfaction rate. CONCLUSION: Concurrent administration of oral mifepristone and vaginal misoprostol is an efficacious regimen for medical abortion of pregnancies

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Available abstract

OBJECTIVE: This study was designed to evaluate the efficacy of using mifepristone and misoprostol concurrently for early medical abortion. MATERIALS AND METHODS: A total of 90 women with undesired pregnancies <or= 49 days' gestation were enrolled. All women concurrently received oral mifepristone 200 mg and vaginal misoprostol 800 microg. Follow-up evaluation with transvaginal ultrasonography was performed 4 days and 2 weeks after treatment. RESULTS: The complete abortion rate was 97.8% (88/90 women). The mean induction to abortion interval was 5.5 hours. The mean bleeding duration was 11.8 days. Patients found the side effects acceptable and reported a 91.1% (82 patients) satisfaction rate. CONCLUSION: Concurrent administration of oral mifepristone and vaginal misoprostol is an efficacious regimen for medical abortion of pregnancies

Key concepts: Misoprostol, Mifepristone, Medical abortion, Medicine, Abortion, Obstetrics, Gestation, Abortifacient

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