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NON-TARGETED EFFECTS OF IONIZING RADIATION: IMPLICATIONS FOR RISK ASSESSMENT AND THE RADIATION DOSE RESPONSE PROFILE

William F. Morgan, Marianne B. Sowa

Open publisher page 65 citations

Abstract

Radiation risks at low doses remain a hotly debated topic. Recent experimental advances in our understanding of effects occurring in the progeny of irradiated cells, and/or the non-irradiated neighbors of irradiated cells (i.e., non-targeted effects associated with exposure to ionizing radiation), have influenced this debate. The goal of this document is to summarize the current status of this debate and speculate on the potential impact of non-targeted effects on radiation risk assessment and the radiation dose response profile.

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What this paper is about

Radiation risks at low doses remain a hotly debated topic. Recent experimental advances in our understanding of effects occurring in the progeny of irradiated cells, and/or the non-irradiated neighbors of irradiated cells (i.e., non-targeted effects associated with exposure to ionizing radiation), have influenced this debate. The goal of this document is to summarize the current status of this debate and speculate on the potential impact of non-targeted effects on radiation risk assessment and the radiation dose response profile.

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OpenAlex reports 65 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Radiation risks at low doses remain a hotly debated topic. Recent experimental advances in our understanding of effects occurring in the progeny of irradiated cells, and/or the non-irradiated neighbors of irradiated cells (i.e., non-targeted effects associated with exposure to ionizing radiation), have influenced this debate. The goal of this document is to summarize the current status of this debate and speculate on the potential impact of non-targeted effects on radiation risk assessment and the radiation dose response profile.

Key concepts: Ionizing radiation, Irradiation, Radiation, Low Dose Radiation, Radiation dose, Radiation exposure, Radiobiology, Medicine

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NON-TARGETED EFFECTS OF IONIZING RADIATION: IMPLICATIONS FOR RISK ASSESSMENT AND THE RADIATION DOSE RESPONSE PROFILE — Research Paper | ScholarLens