2005•Toxicology and Applied PharmacologyRequires access

Arsenic stimulates release of cytochrome from isolated mitochondria via induction of mitochondrial permeability transition

Juan Carlos Bustamante, Leta K. Nutt, Sten Orrenius, Vladimir G. Gogvadze

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Key concepts: Mitochondrial permeability transition pore, Mitochondrion, Mitochondrial apoptosis-induced channel, Cytochrome c, Programmed cell death, Apoptosome, Arsenic trioxide, Apoptosis

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