1988•Transactions of the Royal Society of Tropical Medicine and HygieneRequires access

Detection of parasite related antigens associated with conglutinin binding immune complexes in patients with Schistosoma haematobium

Fabrizio Manca, Roberto Cauda, V. Laghi, Giorgio Trovatello, S Cantarella, Emilio Tresalti, L Ortona, Franco Celada

Abstract

An ELISA assay was designed to detect the presence of parasite related antigens associated with circulating immune complexes in patients affected by urinary schistosomiasis. The assay makes use of bovine conglutinin as the immune complex recognition unit and of human anti-Schistosoma antibody as the antigen recognition unit. Using this method we showed that 10 of 15 (67%) patients with a positive polyethylene glycol assay had circulating immune complexes in which parasite antigens could be detected.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Antigen, Schistosoma haematobium, Immune system, Schistosomiasis, Parasite hosting, Immunology, Schistosoma, Antibody