Lung cancer among asbestos cement workers. A Swedish cohort study and a review.
Carl‐Göran Ohlson, Christer Hogstedt
Abstract
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Carl‐Göran Ohlson, Christer Hogstedt
Abstract
Open-access reader
A cohort study of 1176 Swedish asbestos cement workers did not indicate any asbestos related excess mortality. Possible explanations of the negative outcome are relatively low exposure levels and the predominant use of chrysotile in production. Such a tentative conclusion is supported by a review of five mortality studies of workers exposed to asbestos cement that report considerable differences in relative risks for lung cancer. These differences could be explained by various degrees of cumulative exposure, the amount of amphiboles in the production, and methodological shortcomings. A median exposure of 10-20 fibre-years does not seem to cause an increased risk of lung cancer, particularly when only chrysotile is used.
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A cohort study of 1176 Swedish asbestos cement workers did not indicate any asbestos related excess mortality. Possible explanations of the negative outcome are relatively low exposure levels and the predominant use of chrysotile in production. Such a tentative conclusion is supported by a review of five mortality studies of workers exposed to asbestos cement that report considerable differences in relative risks for lung cancer. These differences could be explained by various degrees of cumulative exposure, the amount of amphiboles in the production, and methodological shortcomings. A median exposure of 10-20 fibre-years does not seem to cause an increased risk of lung cancer, particularly when only chrysotile is used.
Key concepts: Chrysotile, Asbestos, Asbestos cement, Medicine, Lung cancer, Cohort, Cohort study, Environmental health