2005•Cancer CellOpen access

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

Ross L. Levine, Martha Wadleigh, Jan Cools, Benjamin L. Ebert, Gerlinde Wernig, Brian J.P. Huntly, Titus J. Boggon, Iwona Włodarska, Jennifer Clark, Sandra A. Moore, Jennifer Adelsperger, Sumin Koo, Jeffrey C. Lee, Stacey L. Gabriel, Thomas Mercher, Alan D. D’Andrea, Stefan Fröhling, Konstanze Döhner, Peter Marynen, Peter Vandenberghe, Ruben A. Mesa, Ayalew Tefferi, James D. Griffin, Michael J. Eck, William R. Sellers, Matthew M. Meyerson, Todd R. Golub, Stephanie J. Lee, D. Gary Gilliland

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Key concepts: Essential thrombocythemia, Myelofibrosis, Polycythemia vera, Myeloid, Biology, Missense mutation, Cancer research, Mutation