ScholarLens Back to search
1964•ScienceRequires access

Macroglobulin from Human Plasma Which Forms an Enzymatically Active Compound with Trypsin

John W. Mehl, William O'Connell, John DeGroot

Open publisher page 164 citations

Abstract

The protein from human plasma which forms an enzymatically active complex with trypsin and is able to protect trypsin from inhibition by soybean trypsin inhibitor has been shown to be an alpha(2)-macroglobulin. It was obtained from the lipid-poor euglobulin of Cohn Fraction III-0, and appears to be closely related to the 19S-glycoprotein or alpha(2)macroglobulin

About this research paper

What this paper is about

The protein from human plasma which forms an enzymatically active complex with trypsin and is able to protect trypsin from inhibition by soybean trypsin inhibitor has been shown to be an alpha(2)-macroglobulin. It was obtained from the lipid-poor euglobulin of Cohn Fraction III-0, and appears to be closely related to the 19S-glycoprotein or alpha(2)macroglobulin

Why it matters

OpenAlex reports 164 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

The protein from human plasma which forms an enzymatically active complex with trypsin and is able to protect trypsin from inhibition by soybean trypsin inhibitor has been shown to be an alpha(2)-macroglobulin. It was obtained from the lipid-poor euglobulin of Cohn Fraction III-0, and appears to be closely related to the 19S-glycoprotein or alpha(2)macroglobulin

Key concepts: Trypsin, Macroglobulin, Human plasma, Chemistry, Biochemistry, Enzyme, Chromatography

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Macroglobulin from Human Plasma Which Forms an Enzymatically Active Compound with Trypsin — Research Paper | ScholarLens