2006•Toxicology LettersRequires access

Prediction of in vivo embryotoxic effect levels with a combination of in vitro studies and PBPK modelling

Miriam Verwei, Johan A. van Burgsteden, Cyrille A. M. Krul, Johannes J.M. van de Sandt, Andreas P. Freidig

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Key concepts: In silico, In vivo, Physiologically based pharmacokinetic modelling, Retinoic acid, Pharmacology, In vitro, In vitro toxicology, Chemistry

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