2012Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIERequires access

Study of the effects of ionic liquids on lipid bilayers

Taylor T. Young, Stephen Andrew Sarles, Tianyu Wu, Matthew Green, Timothy E. Long, Donald J. Leo

Open publisher page 1 citations

Abstract

The formation of lipid bilayers between ionic liquid droplets is presented as a new means of forming functional bimolecular networks. Ionic liquids are molten salts that have a number of interesting properties, such as the ability to be a liquid at room temperature and exceedingly low vapor pressure. Our research demonstrates that it is possible to consistently and repeatable form lipid bilayers on droplets of ionic liquid solutions. Characterization of the bilayers interfaces shows that the ionic liquids have negligible effects on the stability and electrical properties of the bilayer. It is also shown that the conductance levels in the gating events of Alamethicin peptide are affected by some ionic liquids.

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What this paper is about

The formation of lipid bilayers between ionic liquid droplets is presented as a new means of forming functional bimolecular networks. Ionic liquids are molten salts that have a number of interesting properties, such as the ability to be a liquid at room temperature and exceedingly low vapor pressure. Our research demonstrates that it is possible to consistently and repeatable form lipid bilayers on droplets of ionic liquid solutions. Characterization of the bilayers interfaces shows that the ionic liquids have negligible effects on the stability and electrical properties of the bilayer. It is also shown that the conductance levels in the gating events of Alamethicin peptide are affected by some ionic liquids.

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Available abstract

The formation of lipid bilayers between ionic liquid droplets is presented as a new means of forming functional bimolecular networks. Ionic liquids are molten salts that have a number of interesting properties, such as the ability to be a liquid at room temperature and exceedingly low vapor pressure. Our research demonstrates that it is possible to consistently and repeatable form lipid bilayers on droplets of ionic liquid solutions. Characterization of the bilayers interfaces shows that the ionic liquids have negligible effects on the stability and electrical properties of the bilayer. It is also shown that the conductance levels in the gating events of Alamethicin peptide are affected by some ionic liquids.

Key concepts: Ionic liquid, Alamethicin, Lipid bilayer, Chemical physics, Materials science, Bilayer, Ionic bonding, Conductance

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