Technetium-99m DTP A Localized in Gynecomastia Secondary to Orchiectomy and Estrogen Therapy in a Patient with Carcinoma of the Prostate

Gynecomastia, an enlargement of male breast resulting in response to an excess of estrogen, may occur in a normal condition of puberty and in various pathologic conditions such as Klinefelter's syndrome, testicular neoplasms, or for advanced cirrhosis of the liver. Presented here is a patient with prostatic carcinoma who underwent orchiectomy and recent estrogen therapy in whom gynecomastia developed and during Tc-99m DTPA renal imaging was incidentally found to have symmetrical localization of Tc-99m DTPA in both breasts. Thus, Tc-99m DTPA localization in the breasts may be used as a marker of gynecomastia.