1983Antimicrobial Agents and ChemotherapyOpen access

Comparative in vitro susceptibilities of anaerobic bacteria to cefmenoxime, cefotetan, and N-formimidoyl thienamycin

W.E. Owens, S M Finegold

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Abstract

The in vitro activities of cefmenoxime, cefotetan, and N-formimidoyl thienamycin were compared with those of other antimicrobial agents (metronidazole, clindamycin, cefoxitin, and moxalactam) against anaerobic bacteria. The data obtained indicate that N-formimidoyl thienamycin exhibits excellent activity against anaerobic bacteria; cefotetan and cefmenoxime, though less active, should be of value in treating selected anaerobic infections.

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The in vitro activities of cefmenoxime, cefotetan, and N-formimidoyl thienamycin were compared with those of other antimicrobial agents (metronidazole, clindamycin, cefoxitin, and moxalactam) against anaerobic bacteria. The data obtained indicate that N-formimidoyl thienamycin exhibits excellent activity against anaerobic bacteria; cefotetan and cefmenoxime, though less active, should be of value in treating selected anaerobic infections.

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Available abstract

The in vitro activities of cefmenoxime, cefotetan, and N-formimidoyl thienamycin were compared with those of other antimicrobial agents (metronidazole, clindamycin, cefoxitin, and moxalactam) against anaerobic bacteria. The data obtained indicate that N-formimidoyl thienamycin exhibits excellent activity against anaerobic bacteria; cefotetan and cefmenoxime, though less active, should be of value in treating selected anaerobic infections.

Key concepts: Thienamycin, Cefotetan, Moxalactam, Cefoxitin, Chemistry, Anaerobic bacteria, Microbiology, Clindamycin

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