A randomized double-blind multicentre comparative study of Lamisil(terbinafine) versus ketoconazole in tinea corporis

Seventy-four evaluable patients with dermatophyte infections of skin entered a randomized double-blind study and were treated with 125 mg terbinafine (Lamisil) twice daily (37 patients) or 100 mg ketoconazole twice daily (37 patients). No statistically significant differences in efficacy were found, but the data suggest that Lamisil may have a more rapid onset of action. The Lamisil-treated group continued to improve even after treatment was stopped. Lamisil provoked no rise in liver enzymes. In this study Lamisil was a safe and very effective drug.