2007•Cell Death and DifferentiationRequires access

The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1β processing

Stéphanie Papin, Solange Cuenin, Laetitia Agostini, Fabio Martinon, Sabine Werner, H-D Beer, Christian Grütter, Markus G. Grütter, Jürg Tschopp

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Key concepts: Pyrin domain, Inflammasome, Familial Mediterranean fever, NALP3, MEFV, Caspase 1, Medicine, AIM2

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The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1β processing — Research Paper | ScholarLens