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2014•Nature Reviews Drug DiscoveryOpen access

SCF ubiquitin ligase-targeted therapies

Jeffrey R. Skaar, Julia K. Pagan, Michele Pagano

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Key concepts: Ubiquitin, Ubiquitin ligase, Ubiquitin-Protein Ligases, Proteasome, F-box protein, Protein degradation, Skp1, Computational biology

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