ScholarLens Back to search
2007•The EndocrinologistRequires access

Multiple Morbidities in Acromegaly With Apparently Normal Growth Hormone Levels

Sau Cheung Tiu, Chiu Ming Ng, Chi Chung Shek, Fung Kwan Wong, Hiu Yan Chan, Patrick Chung-Ki Li

Open publisher page 1 citations

Abstract

We present a case of acromegaly with normal growth hormone levels. The patient had markedly elevated IGF-1 and a pituitary microadenoma. He refused all modalities of treatment, and over a span of 30 years the signs and symptoms of acromegaly progressed. This case illustrates the shortcomings of growth hormone–based parameters in the diagnosis of acromegaly and the clinical importance of prolonged elevation of IGF-1. The literature on the diagnostic criteria for acromegaly and on cases of acromegaly without a significant growth hormone elevation is reviewed.

About this research paper

What this paper is about

We present a case of acromegaly with normal growth hormone levels. The patient had markedly elevated IGF-1 and a pituitary microadenoma. He refused all modalities of treatment, and over a span of 30 years the signs and symptoms of acromegaly progressed. This case illustrates the shortcomings of growth hormone–based parameters in the diagnosis of acromegaly and the clinical importance of prolonged elevation of IGF-1. The literature on the diagnostic criteria for acromegaly and on cases of acromegaly without a significant growth hormone elevation is reviewed.

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

We present a case of acromegaly with normal growth hormone levels. The patient had markedly elevated IGF-1 and a pituitary microadenoma. He refused all modalities of treatment, and over a span of 30 years the signs and symptoms of acromegaly progressed. This case illustrates the shortcomings of growth hormone–based parameters in the diagnosis of acromegaly and the clinical importance of prolonged elevation of IGF-1. The literature on the diagnostic criteria for acromegaly and on cases of acromegaly without a significant growth hormone elevation is reviewed.

Key concepts: Acromegaly, Medicine, Growth hormone, Internal medicine, Hormone, Pegvisomant, Endocrinology, Treatment modality

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Multiple Morbidities in Acromegaly With Apparently Normal Growth Hormone Levels — Research Paper | ScholarLens