Influence of lornoxicam a new non‐steroidal antiinflammatory drug on lithium pharmacokinetics
M. Ravic, I G Salas-Herrera, A. E. Johnston, Paul Turner, Kathleen M. Foley, Detlef E. Rosenow
Abstract
M. Ravic, I G Salas-Herrera, A. E. Johnston, Paul Turner, Kathleen M. Foley, Detlef E. Rosenow
Abstract
Abstract The pharmacokinetics of lithium carbonate have been studied in 12 normal young volunteers when given alone and in combination with lornoxicam, a novel non‐steroidal anti‐inflammatory drug. Peak and 12‐h lithium concentrations were significantly higher when both drugs were given together than when lithium was given alone. Caution should be exercised if and when the drugs are co‐prescribed.
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Abstract The pharmacokinetics of lithium carbonate have been studied in 12 normal young volunteers when given alone and in combination with lornoxicam, a novel non‐steroidal anti‐inflammatory drug. Peak and 12‐h lithium concentrations were significantly higher when both drugs were given together than when lithium was given alone. Caution should be exercised if and when the drugs are co‐prescribed.
Key concepts: Lornoxicam, Pharmacokinetics, Lithium carbonate, Lithium (medication), Drug, Pharmacology, Drug interaction, Medicine