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2012•Clinics in Colon and Rectal SurgeryOpen access

Medical Management of Constipation

Meredith Portalatin, Nathaniel S. Winstead

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Abstract

Constipation is a common clinical problem. Initial management of chronic constipation should include lifestyle maneuvers, and increased fiber and fluids. Polyethylene glycol, sodium picosulfate, bisacodyl, prucalopride, lubiprostone, and linaclotide were all more effective than placebo for treating chronic idiopathic constipation. Many commonly used agents lack quality evidence supporting their use.

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What this paper is about

Constipation is a common clinical problem. Initial management of chronic constipation should include lifestyle maneuvers, and increased fiber and fluids. Polyethylene glycol, sodium picosulfate, bisacodyl, prucalopride, lubiprostone, and linaclotide were all more effective than placebo for treating chronic idiopathic constipation. Many commonly used agents lack quality evidence supporting their use.

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OpenAlex reports 173 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Constipation is a common clinical problem. Initial management of chronic constipation should include lifestyle maneuvers, and increased fiber and fluids. Polyethylene glycol, sodium picosulfate, bisacodyl, prucalopride, lubiprostone, and linaclotide were all more effective than placebo for treating chronic idiopathic constipation. Many commonly used agents lack quality evidence supporting their use.

Key concepts: Lubiprostone, Bisacodyl, Constipation, Medicine, Chronic constipation, Placebo, Internal medicine, Gastroenterology

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