2013•Seminars in ImmunopathologyOpen access

Neutrophil proteinase 3 and dipeptidyl peptidase I (cathepsin C) as pharmacological targets in granulomatosis with polyangiitis (Wegener granulomatosis)

Brice Korkmaz, Adam Lesner, Stéphanie Letast, Yassir K. Mahdi, Marie‐Lise Jourdan, Sandrine Dallet‐Choisy, S. Marchand‐Adam, Christine Kellenberger, Marie‐Claude Viaud‐Massuard, Dieter E. Jenne, Francis Gauthier

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Key concepts: Proteinase 3, Azurophilic granule, Cathepsin C, Cathepsin G, Neutrophil elastase, Neutrophil extracellular traps, Proteases, Granulomatosis with polyangiitis