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2000•Planta MedicaRequires access

Cardioactive Terpenoids and a New Rearranged Diterpene fromSalvia syriaca

Ayhan Ulubelen, Sevïl Öksüz, Ufuk Kolak, Hüsniye Birman, Wolfgang Voelter

Open publisher page 34 citations

Abstract

From the roots of Salvia syriaca L., in addition to known terpenoids, a new rearranged diterpene, named salvisyrianone, was isolated. The structure of the new compound was assigned from spectral data. The crude extract and the single compounds were tested for cardiovascular parameters using Wistar Albino rats. Antihypertensive activity was established in the crude extract of the roots as well as in two compounds, ferruginol and 3 beta-hydroxystigmast-5-en-7-one.

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What this paper is about

From the roots of Salvia syriaca L., in addition to known terpenoids, a new rearranged diterpene, named salvisyrianone, was isolated. The structure of the new compound was assigned from spectral data. The crude extract and the single compounds were tested for cardiovascular parameters using Wistar Albino rats. Antihypertensive activity was established in the crude extract of the roots as well as in two compounds, ferruginol and 3 beta-hydroxystigmast-5-en-7-one.

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OpenAlex reports 34 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

From the roots of Salvia syriaca L., in addition to known terpenoids, a new rearranged diterpene, named salvisyrianone, was isolated. The structure of the new compound was assigned from spectral data. The crude extract and the single compounds were tested for cardiovascular parameters using Wistar Albino rats. Antihypertensive activity was established in the crude extract of the roots as well as in two compounds, ferruginol and 3 beta-hydroxystigmast-5-en-7-one.

Key concepts: Diterpene, Terpenoid, Salvia, Traditional medicine, Pharmacognosy, Stereochemistry, Chemistry, Biology

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