ScholarLens Back to search
1984•Photochemistry and PhotobiologyRequires access

PHOTODYNAMIC EFFECTS: PORPHYRIN VS CHLORIN

David Kessel, Christopher J. Dutton

Open publisher page 37 citations

Abstract

Abstract The photosensitizing properties of mesoporphyrin were compared with those of a structurally‐related chlorin, bonellin. Using Sarcoma‐180 tumor cells in culture and irradiation at 610–660 nm, we observed a 10‐fold greater efficiency of photodynamic inactivation by the chlorin. This result was correlated with differences in absorption spectra of the two compounds, not with differences in extent and loci of intracellular accumulation.

About this research paper

What this paper is about

Abstract The photosensitizing properties of mesoporphyrin were compared with those of a structurally‐related chlorin, bonellin. Using Sarcoma‐180 tumor cells in culture and irradiation at 610–660 nm, we observed a 10‐fold greater efficiency of photodynamic inactivation by the chlorin. This result was correlated with differences in absorption spectra of the two compounds, not with differences in extent and loci of intracellular accumulation.

Why it matters

OpenAlex reports 37 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Abstract The photosensitizing properties of mesoporphyrin were compared with those of a structurally‐related chlorin, bonellin. Using Sarcoma‐180 tumor cells in culture and irradiation at 610–660 nm, we observed a 10‐fold greater efficiency of photodynamic inactivation by the chlorin. This result was correlated with differences in absorption spectra of the two compounds, not with differences in extent and loci of intracellular accumulation.

Key concepts: Chlorin, Porphyrin, Photodynamic therapy, Chemistry, Photosensitizer, Photochemistry, Intracellular, Absorption (acoustics)

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
PHOTODYNAMIC EFFECTS: PORPHYRIN VS CHLORIN — Research Paper | ScholarLens