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1970•Journal of General MicrobiologyRequires access

Chemical Characteristics of Endotoxin from Bacteroides fragilis NCTC 9343

Tor Hofstad, T. Kristoffersen

Open publisher page 82 citations

Abstract

SUMMARY:Phenol-water extracted lipopolysaccharides (LPS) from Bacteroides fragilis nctc 9343 did not contain heptose or 2-keto-3-deoxy-octonate. The sugar components identified were glucosamine, galactosamine, glucose, galactose, fucose, rhamnose and traces of mannose. An unidentified amino compound was found. The preparations were free of nucleic acids and protein constituted only a minor fraction of the LPS. The LPS preparations had endotoxic effect when tested in rabbits, but the endotoxic potency was low.

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SUMMARY:Phenol-water extracted lipopolysaccharides (LPS) from Bacteroides fragilis nctc 9343 did not contain heptose or 2-keto-3-deoxy-octonate. The sugar components identified were glucosamine, galactosamine, glucose, galactose, fucose, rhamnose and traces of mannose. An unidentified amino compound was found. The preparations were free of nucleic acids and protein constituted only a minor fraction of the LPS. The LPS preparations had endotoxic effect when tested in rabbits, but the endotoxic potency was low.

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Available abstract

SUMMARY:Phenol-water extracted lipopolysaccharides (LPS) from Bacteroides fragilis nctc 9343 did not contain heptose or 2-keto-3-deoxy-octonate. The sugar components identified were glucosamine, galactosamine, glucose, galactose, fucose, rhamnose and traces of mannose. An unidentified amino compound was found. The preparations were free of nucleic acids and protein constituted only a minor fraction of the LPS. The LPS preparations had endotoxic effect when tested in rabbits, but the endotoxic potency was low.

Key concepts: Rhamnose, Bacteroides fragilis, Heptose, Galactosamine, Fucose, Chemistry, Galactose, Glucosamine

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