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1998•Acta CytologicaRequires access

Cytologic Features of Granulomatous Mastitis

Tadao K. Kobayashi, Hiroyuki Sugihara, Makoto Kato, Shinsuke Watanabe

Open publisher page 19 citations

Abstract

BACKGROUND: Granulomatous mastitis, a rare condition of unknown etiology, affects women of childbearing age and clinically simulates breast carcinoma. CASE: Granulomatous mastitis of the breast in a 32-year-old female was studied by fine needle aspiration cytology. Aspirated material was quite cellular and consisted of epithelioid histiocytes, lymphocytes, plasma cells, neutrophils and multinucleated Langhans-type giant cells. However, no cheesy, necrotic material in the background was noted. CONCLUSION: Granulomatous mastitis, although infrequently reported, appears to have rather characteristic cellular features that may allow its recognition.

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What this paper is about

BACKGROUND: Granulomatous mastitis, a rare condition of unknown etiology, affects women of childbearing age and clinically simulates breast carcinoma. CASE: Granulomatous mastitis of the breast in a 32-year-old female was studied by fine needle aspiration cytology. Aspirated material was quite cellular and consisted of epithelioid histiocytes, lymphocytes, plasma cells, neutrophils and multinucleated Langhans-type giant cells. However, no cheesy, necrotic material in the background was noted. CONCLUSION: Granulomatous mastitis, although infrequently reported, appears to have rather characteristic cellular features that may allow its recognition.

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Available abstract

BACKGROUND: Granulomatous mastitis, a rare condition of unknown etiology, affects women of childbearing age and clinically simulates breast carcinoma. CASE: Granulomatous mastitis of the breast in a 32-year-old female was studied by fine needle aspiration cytology. Aspirated material was quite cellular and consisted of epithelioid histiocytes, lymphocytes, plasma cells, neutrophils and multinucleated Langhans-type giant cells. However, no cheesy, necrotic material in the background was noted. CONCLUSION: Granulomatous mastitis, although infrequently reported, appears to have rather characteristic cellular features that may allow its recognition.

Key concepts: Langhans giant cell, Granulomatous mastitis, Medicine, Giant cell, Histiocyte, Pathology, Mastitis, Epithelioid cell

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