1992•Current Opinion in LipidologyRequires access

Recent developments in low-density lipoprotein apheresis

Thomas Demant, D. Seidel

Abstract

The three established methods for low-density lipoprotein (LDL) apheresis, LDL immunoabsorption, dextran sulfate cellulose-LDL apheresis and heparin-induced extracorporeal LDL precipitation (HELP)-LDL apheresis, are equally safe and effective. Hemorrheological parameters are also improved by these procedures, notably by HELP-LDL apheresis which also eliminates fibrinogen from plasma. Preliminary data suggest that LDL apheresis may be an important tool for primary and secondary prevention in selected patients with a particularly high risk for coronary heart disease

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Key concepts: LDL apheresis, Apheresis, Medicine, Heparin, Fibrinogen, Coronary heart disease, Extracorporeal circulation, Extracorporeal