Genomic Clone OS-2 (D10S20) Detects Different Restriction Fragment Length Polymorphisms in Caucasians and Orientals for Both HindIII and TaqI
Abbas Parsian, Eric J. Devor
Abstract
Abbas Parsian, Eric J. Devor
Abstract
Restriction fragment length polymorphisms (RFLPs) for the anonymous DNA probe OS-2 were studied in a Caucasian population. In a sample of 15 two- and three-generation families and 31 unrelated individuals, the restriction endonuclease TaqI revealed an RFLP not seen in a Japanese sample. A similar situation has been observed for this probe with the restriction endonuclease HindIII.
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Restriction fragment length polymorphisms (RFLPs) for the anonymous DNA probe OS-2 were studied in a Caucasian population. In a sample of 15 two- and three-generation families and 31 unrelated individuals, the restriction endonuclease TaqI revealed an RFLP not seen in a Japanese sample. A similar situation has been observed for this probe with the restriction endonuclease HindIII.
Key concepts: HindIII, TaqI, Restriction enzyme, Restriction fragment length polymorphism, Genetics, Biology, Restriction fragment, genomic DNA