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Complications of Myelography After Partial Metrizamide Withdrawal

Scott D. Hodges, Carl C. Berasi

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Abstract

Lumbar metrizamide myelography (LMM) has been associated with a high incidence of side effects. A total of 94 patients underwent LMM for suspected disc disease or spinal stenosis. In Group 1 a 22-gauge spinal needle was used. Containing the same amount and concentration of metrizamide, an 18-gauge spinal needle was used in Group 2 after which there was partial withdrawal of the metrizamide (average withdrawal: 73%). In Group 1 a total of 38% of patients experienced one side effect whereas 8.5% had two side effects. In Group 2 a total of 8.5% of patients experienced one side effect and 4.25% had two side effects. This study demonstrates a statistically (P less than 0.003) lower incidence of side effects with metrizamide withdrawal after myelography.

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What this paper is about

Lumbar metrizamide myelography (LMM) has been associated with a high incidence of side effects. A total of 94 patients underwent LMM for suspected disc disease or spinal stenosis. In Group 1 a 22-gauge spinal needle was used. Containing the same amount and concentration of metrizamide, an 18-gauge spinal needle was used in Group 2 after which there was partial withdrawal of the metrizamide (average withdrawal: 73%). In Group 1 a total of 38% of patients experienced one side effect whereas 8.5% had two side effects. In Group 2 a total of 8.5% of patients experienced one side effect and 4.25% had two side effects. This study demonstrates a statistically (P less than 0.003) lower incidence of side effects with metrizamide withdrawal after myelography.

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Available abstract

Lumbar metrizamide myelography (LMM) has been associated with a high incidence of side effects. A total of 94 patients underwent LMM for suspected disc disease or spinal stenosis. In Group 1 a 22-gauge spinal needle was used. Containing the same amount and concentration of metrizamide, an 18-gauge spinal needle was used in Group 2 after which there was partial withdrawal of the metrizamide (average withdrawal: 73%). In Group 1 a total of 38% of patients experienced one side effect whereas 8.5% had two side effects. In Group 2 a total of 8.5% of patients experienced one side effect and 4.25% had two side effects. This study demonstrates a statistically (P less than 0.003) lower incidence of side effects with metrizamide withdrawal after myelography.

Key concepts: Metrizamide, Medicine, Myelography, Incidence (geometry), Side effect (computer science), Lumbar, Anesthesia, Lumbar spinal stenosis

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