ScholarLens Back to search
1973•Pesticide ScienceRequires access

Hydrolysis rate and In vitro anticholinesterase activity of fenitrothion and S‐methyl fenitrothion

Jana Kovačičová, V. Bátora, Štefan Truchlik

Open publisher page 17 citations

Abstract

Abstract Anticholinesterase activity in vitro of pure fenitrothion, S‐methyl fenitrothion (SMF) and mixtures of both was studied using different sources of cholinesterase. SMF was two to three orders as active an inhibitor as fenitrothion. In the mixtures, 1 and 5% SMF significantly influenced the I50 value of fenitrothion. The hydrolysis rates of both compounds are given. A method for the synthesis of pure SMF is also described.

About this research paper

What this paper is about

Abstract Anticholinesterase activity in vitro of pure fenitrothion, S‐methyl fenitrothion (SMF) and mixtures of both was studied using different sources of cholinesterase. SMF was two to three orders as active an inhibitor as fenitrothion. In the mixtures, 1 and 5% SMF significantly influenced the I50 value of fenitrothion. The hydrolysis rates of both compounds are given. A method for the synthesis of pure SMF is also described.

Why it matters

OpenAlex reports 17 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Abstract Anticholinesterase activity in vitro of pure fenitrothion, S‐methyl fenitrothion (SMF) and mixtures of both was studied using different sources of cholinesterase. SMF was two to three orders as active an inhibitor as fenitrothion. In the mixtures, 1 and 5% SMF significantly influenced the I50 value of fenitrothion. The hydrolysis rates of both compounds are given. A method for the synthesis of pure SMF is also described.

Key concepts: Fenitrothion, Cholinesterase, Chemistry, Hydrolysis, Organophosphate, In vitro, Chromatography, Organic chemistry

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Hydrolysis rate and In vitro anticholinesterase activity of fenitrothion and S‐methyl fenitrothion — Research Paper | ScholarLens