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1999•Journal of Natural ProductsRequires access

A Cytotoxic Triterpene Saponin from the Root Bark of Aralia dasyphylla

Kai Xiao, Yanghua Yi, Zhong-Zhuang Wang, Haifeng Tang, Yiqing Li, Hou‐Wen Lin

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Abstract

A novel triterpene saponin (1) was isolated from an ethanol extract of the root bark of Aralia dasyphylla. Its structure was elucidated as 3-O-[beta-D-glucopyranosyl (1-->3)-beta-D-galactopyranosyl(1-->2)]-beta-D-glucuronopyranosyl- ole anolic acid-28-O-beta-D-glucopyranoside, according to spectral and chemical evidence. Compound 1 showed significant cytotoxic activity against KB and Hela-S(3) cells.

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What this paper is about

A novel triterpene saponin (1) was isolated from an ethanol extract of the root bark of Aralia dasyphylla. Its structure was elucidated as 3-O-[beta-D-glucopyranosyl (1-->3)-beta-D-galactopyranosyl(1-->2)]-beta-D-glucuronopyranosyl- ole anolic acid-28-O-beta-D-glucopyranoside, according to spectral and chemical evidence. Compound 1 showed significant cytotoxic activity against KB and Hela-S(3) cells.

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OpenAlex reports 23 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

A novel triterpene saponin (1) was isolated from an ethanol extract of the root bark of Aralia dasyphylla. Its structure was elucidated as 3-O-[beta-D-glucopyranosyl (1-->3)-beta-D-galactopyranosyl(1-->2)]-beta-D-glucuronopyranosyl- ole anolic acid-28-O-beta-D-glucopyranoside, according to spectral and chemical evidence. Compound 1 showed significant cytotoxic activity against KB and Hela-S(3) cells.

Key concepts: Triterpene, Saponin, Bark (sound), HeLa, Chemistry, Stereochemistry, Pharmacognosy, Sapogenin

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