2012•Biophysical JournalOpen access

Characterization of a Compound that Reduces Sensitivity to HERG Inhibitors and Prevents hERG-Related, Drug-Induced Arrhythmias in Isolated Rabbit Hearts

F Potet, Amanda Lorinc, Corey R. Hopkins, Raghav Venkataraman, Sébastien Chaigne, Svetlana Z. Stepanovic, Craig W. Lindsley, Franz Baudenbacher, Sabina Kupershmidt

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Key concepts: hERG, Dofetilide, Pharmacology, Chemistry, Cardiotoxicity, Potassium channel blocker, Long QT syndrome, Drug

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Characterization of a Compound that Reduces Sensitivity to HERG Inhibitors and Prevents hERG-Related, Drug-Induced Arrhythmias in Isolated Rabbit Hearts — Research Paper | ScholarLens