2005Biochemical and Biophysical Research CommunicationsRequires access

Feedback regulation of bile acid synthesis in human liver: Importance of HNF-4α for regulation of CYP7A1

Anna Abrahamsson, Ulf Gustafsson, Ewa Ellis, Lisa-Mari Nilsson, Staffan Sahlin, Ingemar Björkhem, Curt Einarsson

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Key concepts: Cholestyramine, Cholesterol 7 alpha-hydroxylase, Bile acid, Chenodeoxycholic acid, Internal medicine, CYP8B1, Enterohepatic circulation, Downregulation and upregulation

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