2011•Advanced materials researchOpen access

Apoptosis of Human Gastric Cancer Cell Line SGC-7901 Induced by Allicin

Shu Li Shao, Wei Wei Zhang, Feng Ying Li

Abstract

To observe the effects of allicin on the growth and apoptosis of gastric cancer cell line. The viability of gastric cancer cell line SGC-7901 was determined by MTT, cell morphology was observed under AO staining and electron microscopy, the apoptosis was measured using flow cytometry analysis. The results indicated that the growth of gastric cancer cell line SGC-7901 was significantly inhibited by allicin, and the IC50 was 80µg/mL. Morphological variations of apoptosis were observed at 48 hours treated with allicin by AO staining and apoptosis body was observed under electron microscope. The results indicated that allicin can suppress the growth of gastric cancer cell line SGC-7901 and induce apoptosis of the cells.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 1 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Allicin, Apoptosis, Cell culture, Staining, MTT assay, Flow cytometry, Cell, Viability assay