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1983•Australian and New Zealand Journal of MedicineRequires access

NEUROLEPTIC MALIGNANT SYNDROME

John D. Scarlett, Robert A. Zimmerman, Samuel F. Berkovic

Open publisher page 35 citations

Abstract

Abstract: Two cases of neuroleptic malignant syndrome (NMS) are presented. This rare pattern of neuroleptic drug toxicity is characterised by fever, muscular rigidity, akinesia and elevated plasma creatine kinase. The condition may be fatal and early recognition is essential. Evidence is presented that NMS is unrelated to malignant hyperpyrexia.

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What this paper is about

Abstract: Two cases of neuroleptic malignant syndrome (NMS) are presented. This rare pattern of neuroleptic drug toxicity is characterised by fever, muscular rigidity, akinesia and elevated plasma creatine kinase. The condition may be fatal and early recognition is essential. Evidence is presented that NMS is unrelated to malignant hyperpyrexia.

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OpenAlex reports 35 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Abstract: Two cases of neuroleptic malignant syndrome (NMS) are presented. This rare pattern of neuroleptic drug toxicity is characterised by fever, muscular rigidity, akinesia and elevated plasma creatine kinase. The condition may be fatal and early recognition is essential. Evidence is presented that NMS is unrelated to malignant hyperpyrexia.

Key concepts: Neuroleptic malignant syndrome, Medicine, Creatine kinase, Muscle Rigidity, Toxicity, Rhabdomyolysis, Drug, Anesthesia

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