2005•NatureRequires access

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

Chloé James, Valérie Ugo, Jean‐Pierre Le Couedic, Judith Staerk, François Delhommeau, Catherine Lacout, Loïc Garçon, Hana Raslová, Roland Berger, Annelise Bennaceur‐Griscelli, Jean‐Luc Villeval, Stefan N. Constantinescu, Nicole Casadevall, William Vainchenker

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Key concepts: Polycythaemia, Polycythemia vera, Janus kinase 2, Myeloproliferative Disorders, Haematopoiesis, Cancer research, Thrombocytosis, Tyrosine kinase