2000•Planta MedicaRequires access

New Pyrrolizidine Alkaloids from Heliotropium crassifolium

Hassan Farsam, Nargess Yassa, Parisa Sarkhail, Abbas Shafiee

Abstract

Heliotropium crassifolium Boiss, (Boraginaceae) from a population of Ilam, western region of Iran was studied for pyrrolizidine alklaoids (PAs). Four alkaloids have been identified: europine 1, europine N-oxide 2 and a new pyrrolizidine alkaloids ilamine 3 and its N-oxide 4, respectively. Their structures were elucidated by IR, 1H-NMR and EIMS data.

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Key concepts: Pyrrolizidine, Boraginaceae, Traditional medicine, Population, Chemistry, Botany, Biology, Stereochemistry