ScholarLens Back to search
1974•Acta Medica ScandinavicaRequires access

CORTISOL AND CORTISONE ACETATE IN PARENTERAL GLUCOCORTICOID THERAPY?

Henrik Kehlet, S. Nistrup Madsen, C Binder

Open publisher page 16 citations

Abstract

Abstract. Intramuscular cortisol and cortisone acetate have been administered to six patients with adrenocortical insufficiency. Plasma cortisol determinations during the following four hours showed a pronounced increase after injection of cortisol, but virtually no increase in five and only a moderate increase in one patient after injection of cortisone acetate. It is therefore recommended not to use cortisone acetate in parenteral glucocorticoid therapy.

About this research paper

What this paper is about

Abstract. Intramuscular cortisol and cortisone acetate have been administered to six patients with adrenocortical insufficiency. Plasma cortisol determinations during the following four hours showed a pronounced increase after injection of cortisol, but virtually no increase in five and only a moderate increase in one patient after injection of cortisone acetate. It is therefore recommended not to use cortisone acetate in parenteral glucocorticoid therapy.

Why it matters

OpenAlex reports 16 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Abstract. Intramuscular cortisol and cortisone acetate have been administered to six patients with adrenocortical insufficiency. Plasma cortisol determinations during the following four hours showed a pronounced increase after injection of cortisol, but virtually no increase in five and only a moderate increase in one patient after injection of cortisone acetate. It is therefore recommended not to use cortisone acetate in parenteral glucocorticoid therapy.

Key concepts: Cortisone, Cortisone acetate, Medicine, Glucocorticoid, Endocrinology, Internal medicine, Intramuscular injection, Desoxycorticosterone Acetate

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
CORTISOL AND CORTISONE ACETATE IN PARENTERAL GLUCOCORTICOID THERAPY? — Research Paper | ScholarLens