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2012•The Pediatric Infectious Disease JournalOpen access

Bacterial Meningitis and Pneumococcal Serotype Distribution in Children in Cameroon

Alain Gervaix, Jean Taguebue, Béatrice Ninet Bescher, Jacques Corbeil, Frédéric Raymond, Gabriel Alcoba, Marie Kobela, Tetanye Ekoe

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Abstract

Acute bacterial meningitis causes a substantial number of deaths in Cameroon. Among 170 children with acute meningitis, 112 were positive for a bacterial pathogen when tested using polymerase chain reaction amplification, and Streptococcus pneumoniae accounted for 57.1% of cases. Pneumococcal serotype coverage by 13-valent pneumococcal conjugate vaccine was 62.1%. This study shows that in Cameroon, 13-valent pneumococcal conjugate vaccine coverage is less than what is estimated for other African countries.

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What this paper is about

Acute bacterial meningitis causes a substantial number of deaths in Cameroon. Among 170 children with acute meningitis, 112 were positive for a bacterial pathogen when tested using polymerase chain reaction amplification, and Streptococcus pneumoniae accounted for 57.1% of cases. Pneumococcal serotype coverage by 13-valent pneumococcal conjugate vaccine was 62.1%. This study shows that in Cameroon, 13-valent pneumococcal conjugate vaccine coverage is less than what is estimated for other African countries.

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Available abstract

Acute bacterial meningitis causes a substantial number of deaths in Cameroon. Among 170 children with acute meningitis, 112 were positive for a bacterial pathogen when tested using polymerase chain reaction amplification, and Streptococcus pneumoniae accounted for 57.1% of cases. Pneumococcal serotype coverage by 13-valent pneumococcal conjugate vaccine was 62.1%. This study shows that in Cameroon, 13-valent pneumococcal conjugate vaccine coverage is less than what is estimated for other African countries.

Key concepts: Streptococcus pneumoniae, Serotype, Pneumococcal conjugate vaccine, Meningitis, Medicine, Virology, Polymerase chain reaction, Conjugate vaccine

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