1999•Pharmacy and Pharmacology CommunicationsRequires access

Simultaneous Determination of Amlodipine–Enalapril Maleate and Amlodipine–Lisinopril in Combined Tablet Preparations by Derivative Spectrophotometry

C. V. N. Prasad, Ranendra Narayan Saha, P. Parimoo

Abstract

A derivative spectrophotometric procedure for the simultaneous determination of amlodipine with either enalapril maleate or lisinopril in combined tablet preparations was developed. Tablet extracts of amlodipine-enalapril maleate and amlodipine-lisinopril were prepared in 0–1 M HCl. The zero-crossing point technique was used to estimate the amounts of individual drugs in the combined preparations. The results were found to be accurate, reproducible and free from interference.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 40 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Lisinopril, Amlodipine, Enalapril, Enalapril Maleate, Chemistry, Chromatography, Spectrophotometry, Pharmacology