2013•University of Twente Research InformationRequires access

Localisation of the subthalamic nucleus in Parkinson's disease with neural beta and gamma activity of local field potentials

Rens Verhagen, Daphne G.M. Zwartjes, Tjitske Heida, Maria Fiorella Contarino, Rob M.A. de Bie, Pepijn van den Munckhof, P.R. Schuurman, H.C.F. Martens, Petrus H. Veltink, Lo J. Bour

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Abstract

To evaluate the nature of oscillatory activity in the subthalamic nucleus (STN) by means of intraoperative local field potential (LFP) recordings, its relationship with microelectrode recordings (MER) and its potential use to locate the STN and its sensorimotor sub-area in patients with Parkinson’s disease during deep brain stimulation (DBS) surgery.

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Key concepts: Subthalamic nucleus, Local field potential, Deep brain stimulation, Parkinson's disease, Neuroscience, Beta Rhythm, Psychology, Medicine