2014•Applied Mechanics and MaterialsOpen access

In Vivo Antioxidant Activity of Black Soybean Peptide in Aging Mice Caused by D-Galactose

Yong Hua Wu, Enqi Liu, Jian Ping Zhang, Shang Long Chen, Yong Li, Zhong Hua Geng

Abstract

Black soybean peptides (BSPs) with potent antioxidant activity were purified from black soybean protein hydrolysates (BSH) by using the ultrafiltration (UF) and macroporous adsorption resin (MAR), and in vivo antioxidant activity of the fraction BSP-DA-c was evaluated in aging mice induced by D-galactose. The results showed that orally administration of BSP-DA-c fraction at the dose of 500 and 1000 mg/kg per day could remarkably increase (P<0.05) the activity of SOD and GSH-Px in liver and the activity of GSH-Px in serum, the contents of MDA in serum and liver were reduced significantly (P<0.05), inferred that BSP-DA-c had strong antioxidant activity in mice.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 6 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Antioxidant, In vivo, Chemistry, Hydrolysate, Galactose, Ultrafiltration (renal), Peptide, Glutathione