2013•The Journal of PediatricsOpen access

Breakthrough Varicella in a Cancer Patient with Persistent Varicella Antibody after One Varicella Vaccination

Masaki Yamada, Natalie L. Kamberos, Charles F. Grose

Abstract

A boy with Hodgkin disease contracted breakthrough varicella from his father, who had chickenpox. The boy had received a single varicella vaccination and was seropositive by enzyme-linked immunosorbent assay before being diagnosed with breakthrough varicella. Seropositivity after a single varicella vaccination does not guarantee complete protection in an immunocompromised child.

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Key concepts: Medicine, Chickenpox, Varicella vaccine, Chickenpox Vaccine, Vaccination, Pediatrics, Antibody, Virology