Cutaneous Lymphomas Consist of a Spectrum of Nosologically Different Entities Including Mycosis Fungoides and Small Plaque Parapsoriasis
Günter Burg
Abstract
Günter Burg
Abstract
BROCQ IN his article on parapsoriasis,1based on Unna's original observation,2describes a distinct small plaque form characterized by well-defined plaques, 2 to 6 cm in diameter (plaques circonscites, assez bien limitées, de 2 a 6 cm de diametre). This disease has been recognized since then as an entity by many authorities in both dermatology and dermatopathology.3-6Ackerman et al7-9claim that small plaque (digitate) parapsoriasis (SPP) must be mycosis fungoides (MF). Haeffner et al10came to the conclusion that some cases of SPP show a dominant T-cell clone (results confirmed by further unpublished data). Burg and Dummer11state that SPP is an "abortive" cutaneous T-cell lymphoma (CTCL) kept in a biologically silent stage, but it is not MF. IS MF A CTCL? Mycosis fungoides can be defined as a peripheral non-Hodgkin's T-cell lymphoma initially and preferentially presenting in the skin, showing
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BROCQ IN his article on parapsoriasis,1based on Unna's original observation,2describes a distinct small plaque form characterized by well-defined plaques, 2 to 6 cm in diameter (plaques circonscites, assez bien limitées, de 2 a 6 cm de diametre). This disease has been recognized since then as an entity by many authorities in both dermatology and dermatopathology.3-6Ackerman et al7-9claim that small plaque (digitate) parapsoriasis (SPP) must be mycosis fungoides (MF). Haeffner et al10came to the conclusion that some cases of SPP show a dominant T-cell clone (results confirmed by further unpublished data). Burg and Dummer11state that SPP is an "abortive" cutaneous T-cell lymphoma (CTCL) kept in a biologically silent stage, but it is not MF. IS MF A CTCL? Mycosis fungoides can be defined as a peripheral non-Hodgkin's T-cell lymphoma initially and preferentially presenting in the skin, showing
Key concepts: Mycosis fungoides, Medicine, Cutaneous T-cell lymphoma, Dermatology, Peripheral T-cell lymphoma, Lymphoma, clone (Java method), Dermatopathology