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Autoimmune Hemolytic Anemia Due to Levodopa Therapy

Mary Territo

Abstract

A 67-year-old white man developed Coombs test-positive hemolytic anemia secondary to levodopa therapy for Parkinson disease. The initial episode of anemia occurred after 11 months and 660 gm of drug exposure. A warm autoantibody directed against the Rh locus was found in the patient's serum and on his erythrocytes. On discontinuance of levodopa therapy, the autoimmune hemolytic anemia abated.

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Available abstract

Key concepts: Medicine, Autoimmune hemolytic anemia, Anemia, Hemolytic anemia, Autoantibody, Levodopa, Immunology, Disease