2009•Chemical CommunicationsRequires access

Molecular beacon-functionalized gold nanoparticles as probes in dry-reagent strip biosensor for DNA analysis

Xun Mao, Hui Xu, Qingxiang Zeng, Lingwen Zeng, Guodong Liu

Abstract

The highly specific molecule recognition properties of molecular beacons (MB) are combined with the unique optical properties of gold nanoparticles (Au-NPs) for the development of a dry-reagent strip-type nucleic acid biosensor (DSNAB) that enables sensitive and low-cost detection of nucleic acid samples within 15 min.

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Available abstract

Key concepts: Molecular beacon, Nucleic acid, Colloidal gold, Reagent, Biosensor, Nanoparticle, Nanotechnology, Chemistry