I1171 missense mutation (particularly I1171N) is a common resistance mutation in ALK-positive NSCLC patients who have progressive disease while on alectinib and is sensitive to ceritinib
Sai‐Hong Ignatius Ou, Joel Greenbowe, Ziad U. Khan, Michele C. Azada, Jeffrey S. Ross, Phil J. Stevens, Siraj M. Ali, Vincent A. Miller, Barbara J. Gitlitz
Abstract